For research purposes only
MT-1
MT-1 (Melanotan I, afamelanotide) is a linear alpha-MSH analog (CAS 75921-69-6) modified with a Nle4, D-Phe7 substitution pattern that increases MC1R binding affinity and confers resistance to DPP-IV cleavage relative to native alpha-MSH. In melanocyte culture models it serves as the reference agonist for MC1R pharmacology and for probing the eumelanin synthesis pathway through the cAMP-MITF-MC1R cascade. Its linear architecture and focused receptor selectivity distinguish it from cyclic Melanotan 2 as a tool for isolating individual melanocortin receptor subtype contributions. Supplied lyophilized for in vitro research use only.
Select size
$35.00
Specifications
- CAS
- 75921-69-6
- MW
- 1646.87 g/mol
- Formula
- C78H111N21O19
- Purity
- >=99.6 HPLC
- Storage
- -20 °C, lyophilized
Research Notes
What is MT-1?
MT-1 is a synthetic research compound studied in laboratory settings. It has molecular formula C78H111N21O19, a molecular weight of 1646.87 g/mol, CAS 75921-69-6. It is intended for in vitro research use only and is not for human or animal use.
What purity is METATIDE's MT-1?
METATIDE supplies MT-1 at >=99.6% purity, verified by third-party HPLC analysis. A certificate of analysis is available on request.
How is MT-1 supplied?
MT-1 is supplied as a lyophilized powder in sealed research-grade vials, stored -20 °C, lyophilized, intended for in vitro and laboratory research use only.