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METATIDE
MOTS-c

For research purposes only

MOTS-c

MOTS-c is a 16-amino acid peptide encoded within the 12S rRNA region of the mitochondrial genome, a distinction that earned it recognition as the first mitochondrial-derived peptide (MDP) with documented systemic metabolic signaling activity. In skeletal muscle and adipocyte cultures it activates AMPK, upregulates FGF21 expression, and enhances glucose uptake through insulin-independent pathways. Its mitochondrial genome origin provides a singular vantage point for studying retrograde mito-nuclear communication and metabolic homeostasis at the intercellular signaling level. Supplied lyophilized for in vitro research use only.

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$55.00

Specifications

CAS
1627580-64-6
MW
2174.59 g/mol
Formula
C100H152N28O22S2
Purity
>=99.3 HPLC
Storage
-20 °C, lyophilized

Research Notes

What is MOTS-c?

MOTS-c is a synthetic research compound studied in laboratory settings. It has molecular formula C100H152N28O22S2, a molecular weight of 2174.59 g/mol, CAS 1627580-64-6. It is intended for in vitro research use only and is not for human or animal use.

What purity is METATIDE's MOTS-c?

METATIDE supplies MOTS-c at >=99.3% purity, verified by third-party HPLC analysis. A certificate of analysis is available on request.

How is MOTS-c supplied?

MOTS-c is supplied as a lyophilized powder in sealed research-grade vials, stored -20 °C, lyophilized, intended for in vitro and laboratory research use only.