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METATIDE
GLP-1(S)

For research purposes only

GLP-1(S)

GLP-1(S) (Semaglutide) is a synthetic GLP-1 receptor agonist with 94% sequence homology to native GLP-1 7-36 amide, distinguished by a C18 fatty di-acid chain at Lys26 and an Aib substitution at position 8 that confers DPP-IV resistance. The fatty acid modification enables reversible albumin binding, translating to a pharmacokinetic half-life far extended beyond native GLP-1 in model systems. It is the established research standard for long-acting GLP-1R agonism, receptor internalization kinetics, and beta-cell cAMP signaling characterization. Supplied lyophilized for in vitro research use only.

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$170.00

Specifications

CAS
910463-68-2
MW
4113.58 g/mol
Formula
C187H291N45O59
Purity
>=99.0 HPLC
Storage
-20 °C, lyophilized

Research Notes

What is GLP-1(S)?

GLP-1(S) is a synthetic research compound studied in laboratory settings. It has molecular formula C187H291N45O59, a molecular weight of 4113.58 g/mol, CAS 910463-68-2. It is intended for in vitro research use only and is not for human or animal use.

What purity is METATIDE's GLP-1(S)?

METATIDE supplies GLP-1(S) at >=99.0% purity, verified by third-party HPLC analysis. A certificate of analysis is available on request.

How is GLP-1(S) supplied?

GLP-1(S) is supplied as a lyophilized powder in sealed research-grade vials, stored -20 °C, lyophilized, intended for in vitro and laboratory research use only.