For research purposes only
FOXO4
FOXO4-DRI is a D-amino acid retro-inverso peptide engineered to replicate the FOXO4 interaction domain responsible for sequestering p53 inside senescent cells. Competitive displacement of the endogenous FOXO4-p53 complex selectively triggers apoptosis in p21-high senescent cells in preclinical culture models, making it a precise molecular lever for isolating senolytic activity. The compound has become the field's reference tool for mechanistic studies of cellular senescence pathways. Supplied lyophilized for in vitro research use only.
Select size
$200.00
Specifications
- CAS
- 2460055-10-9
- MW
- 5358.06 g/mol
- Formula
- C228H388N86O64
- Purity
- >=99.0 HPLC
- Storage
- -20 °C, lyophilized
Research Notes
What is FOXO4?
FOXO4 is a synthetic research compound studied in laboratory settings. It has molecular formula C228H388N86O64, a molecular weight of 5358.06 g/mol, CAS 2460055-10-9. It is intended for in vitro research use only and is not for human or animal use.
What purity is METATIDE's FOXO4?
METATIDE supplies FOXO4 at >=99.0% purity, verified by third-party HPLC analysis. A certificate of analysis is available on request.
How is FOXO4 supplied?
FOXO4 is supplied as a lyophilized powder in sealed research-grade vials, stored -20 °C, lyophilized, intended for in vitro and laboratory research use only.